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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE4A
All Species:
35.15
Human Site:
T459
Identified Species:
55.24
UniProt:
Q14139
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14139
NP_004779.2
1066
122561
T459
P
R
S
S
R
L
L
T
F
N
P
T
Y
C
A
Chimpanzee
Pan troglodytes
XP_001161169
1066
122495
T459
P
R
S
S
R
L
L
T
F
N
P
T
Y
C
A
Rhesus Macaque
Macaca mulatta
XP_001097812
1067
122494
T459
P
R
S
S
R
L
L
T
F
N
P
T
Y
C
A
Dog
Lupus familis
XP_850081
1066
122542
T459
P
R
S
S
R
L
L
T
F
N
P
T
Y
C
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9ES00
1173
133285
D594
C
R
I
T
L
P
N
D
E
T
R
I
N
A
T
Rat
Rattus norvegicus
Q6P7A2
1066
122361
T459
P
R
S
S
R
L
L
T
F
N
P
T
Y
C
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001026081
1074
123247
T460
P
K
S
P
K
L
L
T
F
N
P
T
Y
C
A
Frog
Xenopus laevis
NP_001084506
1072
122544
T458
P
R
S
A
R
L
L
T
F
N
P
T
Y
C
A
Zebra Danio
Brachydanio rerio
XP_001922961
1078
122949
T464
P
Y
S
P
K
L
L
T
F
N
P
T
Y
C
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609060
993
113046
I423
K
Y
N
F
V
T
E
I
F
Y
M
T
H
K
C
Honey Bee
Apis mellifera
XP_393070
965
109934
L399
S
I
N
S
I
I
H
L
K
G
M
T
S
E
T
Nematode Worm
Caenorhab. elegans
Q09349
980
113212
A426
M
D
E
S
G
A
V
A
F
A
S
Q
F
A
D
Sea Urchin
Strong. purpuratus
XP_786748
942
107668
T424
P
D
T
T
N
I
M
T
V
D
M
S
Y
G
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LF41
1038
117510
S457
T
S
S
S
S
N
A
S
G
Q
N
A
K
S
A
Baker's Yeast
Sacchar. cerevisiae
P54860
961
109887
T400
L
H
Y
G
L
G
G
T
L
S
F
E
E
K
M
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.1
98.6
N.A.
24.6
97
N.A.
N.A.
87.7
79.7
76.7
N.A.
33.1
36.5
22.9
32.7
Protein Similarity:
100
100
98.5
99.4
N.A.
45.2
99
N.A.
N.A.
94.3
90.8
87.4
N.A.
51.3
54.5
42.5
52.2
P-Site Identity:
100
100
100
100
N.A.
6.6
93.3
N.A.
N.A.
80
93.3
73.3
N.A.
13.3
13.3
13.3
20
P-Site Similarity:
100
100
100
100
N.A.
13.3
93.3
N.A.
N.A.
93.3
100
80
N.A.
26.6
26.6
26.6
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
25.3
22.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
43.9
41.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
7
0
7
7
7
0
7
0
7
0
14
47
% A
% Cys:
7
0
0
0
0
0
0
0
0
0
0
0
0
54
7
% C
% Asp:
0
14
0
0
0
0
0
7
0
7
0
0
0
0
7
% D
% Glu:
0
0
7
0
0
0
7
0
7
0
0
7
7
7
0
% E
% Phe:
0
0
0
7
0
0
0
0
67
0
7
0
7
0
0
% F
% Gly:
0
0
0
7
7
7
7
0
7
7
0
0
0
7
0
% G
% His:
0
7
0
0
0
0
7
0
0
0
0
0
7
0
0
% H
% Ile:
0
7
7
0
7
14
0
7
0
0
0
7
0
0
0
% I
% Lys:
7
7
0
0
14
0
0
0
7
0
0
0
7
14
0
% K
% Leu:
7
0
0
0
14
54
54
7
7
0
0
0
0
0
7
% L
% Met:
7
0
0
0
0
0
7
0
0
0
20
0
0
0
7
% M
% Asn:
0
0
14
0
7
7
7
0
0
54
7
0
7
0
0
% N
% Pro:
60
0
0
14
0
7
0
0
0
0
54
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% Q
% Arg:
0
47
0
0
40
0
0
0
0
0
7
0
0
0
0
% R
% Ser:
7
7
60
54
7
0
0
7
0
7
7
7
7
7
7
% S
% Thr:
7
0
7
14
0
7
0
67
0
7
0
67
0
0
14
% T
% Val:
0
0
0
0
7
0
7
0
7
0
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
14
7
0
0
0
0
0
0
7
0
0
60
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _